This protocol applies to patients with central nervous system Whipple disease (CNS-WD) who present with hydrocephalus — a complication that requires evaluation and management beyond systemic antibiotic therapy alone.
When Whipple's disease spreads to the central nervous system and causes hydrocephalus, the altered cerebrospinal fluid dynamics must be addressed as part of the overall treatment plan.
In this setting, management includes a neurosurgical intervention to manage CSF flow. The complete protocol — including the specific procedure and full clinical guidance — is available via the link below.
In patients with CNS-WD and hydrocephalus, neruosurgery is required for placement of ventriculoperitoneal shunt (VPS).
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