Treatment of Vulvovaginal Candidiasis During Pregnancy

Vulvovaginal candidiasis in pregnancy requires a treatment approach chosen with foetal safety in mind. The selection of local therapy is guided by trimester, as certain agents carry specific considerations early in pregnancy.

Clinical Scenario

This protocol applies to pregnant patients with vulvovaginal candidiasis. Local treatment is preferred throughout pregnancy. The first trimester carries particular clinical weight: treatment choices during this period are made to avoid foetal malformations and miscarriage.

Treatment Approach

Local therapy is the cornerstone of management in this setting. The primary agent recommended — especially in the first trimester — is a locally applied option; an alternative local agent exists for situations where the primary choice is not appropriate. The complete regimen, selection criteria, and trimester-specific guidance are available in the full protocol.

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References

DOI: 10.1111/myc.13248

Local treatment is preferred during pregnancy.
Treatment for vulvovaginal candidosis during pregnancy should involve local clotrimazole, especially during the first trimester, in order to avoid foetal malformations and miscarriage.
Therefore, dequalinium chloride might be a therapeutic option for VVC during pregnancy.

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