Treatment of Local Vulvar/Perineal Recurrence of Squamous Cell Carcinoma of the Vulva

This protocol applies to patients with local recurrence of squamous cell carcinoma at the vulvar or perineal site. Such recurrences may in some cases represent new primary disease arising from underlying pre-malignant skin conditions, which has direct implications for how re-staging is approached.

Nodal status at the inguinofemoral region is a critical factor at the time of recurrence. Clinically negative inguinofemoral lymph nodes warrant specific consideration regarding the need for groin re-staging before proceeding.

The primary intervention in this setting is surgical, targeting the recurrent vulvar tumor. The full protocol specifies the extent of resection and defines the conditions under which additional nodal evaluation is incorporated into the management plan.