Surgical Treatment for Stable, Localized Non-Segmental Vitiligo After Medical Interventions Have Failed

This protocol applies to patients with stable, localized non-segmental vitiligo whose disease has not responded adequately to medical interventions, and who have a negative history of Koebner phenomenon. These criteria define the specific population for whom a surgical pathway becomes appropriate.

Surgical intervention is the cornerstone of this protocol, encompassing tissue- and cell-based grafting techniques delivered to stabilised lesions. Several distinct surgical modalities are covered — the complete regimen, including selection criteria between techniques and procedural guidance, is available in the full protocol.

Technique-specific eligibility, sequencing, and procedural detail are contained in the complete protocol below.