Treatment of Vitamin B3 Deficiency in Hartnup's Disease

This protocol addresses vitamin B3 deficiency occurring in the context of Hartnup's disease, a specific clinical setting that shapes both the management goals and the long-term treatment strategy.

In patients with Hartnup's disease, niacinamide therapy is an effective approach to managing the resulting vitamin B3 deficiency. The condition-specific nature of the deficiency makes targeted, ongoing supplementation the cornerstone of care.

Management involves lifelong niacinamide supplementation, adjusted to each patient's clinical response. The complete structured regimen — including the full dosing framework and clinical decision points — is available in the protocol.

Full dosing guidance and the complete algorithm are behind the link below.