Uterine leiomyosarcoma (uLMS) is the principal histological subtype within the uterine sarcoma group. This protocol defines the treatment approach for patients with a confirmed uLMS diagnosis presenting with localized, stage I disease.
Uterine leiomyosarcomas represent the main subgroup of uterine sarcomas. This protocol applies specifically to patients with uLMS in a localized setting, where the disease is confined to the uterus at initial presentation.
For localized stage I disease, the treatment strategy is anchored by a specific surgical intervention. The complete protocol details both the operative standard of care and the precise role assigned to adjuvant therapies — including what is and is not considered standard in this setting.