Low-grade endometrial stromal sarcoma (LG-ESS) represents a specific subtype of uterine sarcoma with distinct clinical and histological characteristics. This protocol addresses first-line management in this setting.
LG-ESS accounts for approximately 20% of all uterine sarcomas and is typically diagnosed at a mean age of around 50 years. The appropriate treatment strategy is determined by disease stage and the low-grade histological profile of this subtype.
For localized disease, the cornerstone of management is a surgical approach. The full protocol defines the recommended operative strategy and specifies the evidence-based guidance on adjuvant options at this stage.
DOI: 10.1136/ijgc-2024-005823