Urogenital trichomoniasis
ICD-10 A59.0; A59.9 · ICD-11 1A92

Treatment of Urogenital Trichomoniasis in First-Trimester Pregnancy

Urogenital trichomoniasis presenting during pregnancy, and specifically during the first trimester, requires a management approach that accounts for the unique constraints of early gestation. Standard systemic treatment options may not be appropriate at this stage, so the choice of therapy is guided by safety in early pregnancy.

Clinical scenario Urogenital trichomoniasis in a patient who is pregnant and in the first trimester. The first trimester period shapes which therapeutic options are considered appropriate.
Approach Local intravaginal therapy can be considered during the first trimester to provide temporary symptom relief while systemic options remain limited at this gestational stage. Full regimen details, dosing, and duration are in the structured protocol below.
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References

DOI: 10.1128/cmr.00109-16

During pregnancy, a daily dose of 100 mg of clotrimazole can be delivered intravaginally at bedtime for 14 days and can provide temporary relief to patients in the first trimester.

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