Treatment of Recurrent or Resistant Urogenital Trichomoniasis
Recurrent or resistant urogenital trichomoniasis presents a distinct clinical challenge. When the infection persists or returns, an intensified treatment approach is warranted in place of a standard short course.
Clinical Scenario
This protocol addresses urogenital trichomoniasis that recurs or fails to clear — infections for which a standard-duration regimen has proved insufficient and a more sustained therapeutic effort is required.
Treatment Approach
Management involves oral metronidazole or tinidazole at higher doses over extended periods, combined with intravaginal treatment. The complete regimen — specific doses, duration, and sequencing — is detailed in the full protocol.
References
DOI: 10.1128/cmr.00109-16
- In fact, recurrent or resistant trichomoniasis infections are treated for longer periods with increasing doses of metronidazole.
- Different treatment options with higher doses of oral metronidazole or tinidazole for longer periods have been used together with intravaginal drug delivery.