This protocol applies to uncomplicated enteric fever where susceptibility testing confirms the infecting organism is not susceptible to ciprofloxacin but remains susceptible to ceftriaxone. Patients with uncomplicated enteric fever can be managed at home with reliable care and close medical follow-up for complications or failure to respond to therapy.
Susceptibility to ciprofloxacin is absent in this scenario, making fluoroquinolone therapy inappropriate. Ceftriaxone susceptibility is confirmed, and treatment must be tailored to this susceptibility profile.
When susceptibility results confirm ciprofloxacin non-susceptibility and retained ceftriaxone activity, an IV cephalosporin forms the basis of treatment, with duration guided by patient group. An oral macrolide is available as an alternative in appropriate cases. The complete regimen — including age-specific dosing, route, frequency, and duration — is available in the structured protocol.
Patients with uncomplicated enteric fever can be managed at home with oral antibiotics, reliable care and close medical follow-up for complications or failure to respond to therapy.
Not susceptible to ciprofloxacin, but susceptible to ceftriaxone.
When antimicrobial susceptibility results are available, the treatment can be tailored accordingly.
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