This protocol applies to patients with severe or complicated enteric fever — including those with severe illness, inability to tolerate oral treatment due to vomiting and/or severe diarrhoea, or intestinal and extra-intestinal complications — where the infecting organism is susceptible to ciprofloxacin. These patients typically require hospitalisation and parenteral antimicrobial treatment.
When the causative organism is ciprofloxacin-susceptible, parenteral ciprofloxacin-based antimicrobial therapy is the recommended approach for severe enteric fever, with the full protocol specifying management across paediatric and adult patients and addressing life-threatening intestinal complications.