What Is the Treatment for Thromboembolism of Lower Limb Arteries?

Thromboembolism of the lower limb arteries requires anticoagulation therapy to prevent further thromboembolic events. The choice of agent and monitoring approach depends on individual clinical factors — the full protocol addresses these in detail.

Treatment Approach

Full-dose anticoagulation is indicated. Direct oral anticoagulants are the preferred first-line option for eligible patients; an alternative regimen is also available depending on individual clinical circumstances.

Clinical Target

When warfarin is used, the goal is a therapeutic international normalized ratio (INR) of 2.0–3.0.

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References

DOI: 10.3389/fcvm.2021.773214

Patiens with cardiogenic embolization to lower extremity arteries should be recommended anticoagulant treatment with either one of the DOACs (apixaban, dabigatran, edoxaban, and rivaroxaban) or warfarin.
Direct oral anticoagulant, the thrombin inhibitor dabigatran or one of the factor Xa-inhibitors rivaroxaban, edoxaban, and apixaban are first hand alternatives for anticoagulation.
The therapeutic target is an international normalized ratio (INR) of 2.0-3.0.

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