What Is the Treatment of Tetralogy of Fallot with Residual Ventricular Septal Defect and Significant Left Ventricular Volume Overload?

This protocol applies to patients with Tetralogy of Fallot who have a residual ventricular septal defect (VSD) accompanied by significant left ventricular volume overload, or who are undergoing pulmonary valve surgery in the same setting.

The combination of a residual VSD and haemodynamically meaningful left ventricular volume overload — or the concurrent need for pulmonary valve intervention — identifies a specific subset of post-repair Tetralogy of Fallot patients for whom further structural management warrants consideration.

Management in this scenario involves a surgical approach directed at the septal defect. The complete structured regimen — including thresholds for intervention, procedural details, and follow-up criteria — is available in the full protocol.