This protocol addresses the specific clinical situation where germ cell neoplasia in situ (GCNIS) is identified in a patient's only remaining testis — the contralateral testis being absent. Managing this condition requires a carefully calibrated approach, as treatment is directed at the sole organ.
Germ cell neoplasia in situ (GCNIS) detected in a solitary testis, with no contralateral testis present. The absence of the contralateral testis substantially narrows the treatment options and demands particular attention to long-term functional consequences.
Current evidence supports a localised, radiation-based intervention directed at the affected testis. The specific parameters, fractionation details, and complete clinical algorithm are available in the structured protocol.
Eradication of germ cell neoplasia in situ, confirmed on repeat testicular biopsy.