Treatment of Systemic Sclerosis with Small Intestinal Bacterial Overgrowth

This protocol addresses patients with systemic sclerosis who have concurrent small intestinal bacterial overgrowth (SIBO). Appropriate treatment of SIBO is an important component of managing this population.

Management involves a rotating antibiotic strategy directed at intestinal bacterial overgrowth — the complete regimen, sequencing, and clinical decision points are contained in the full protocol.