Systemic sclerosis
ICD-10 M34 · ICD-11 4A42

Treatment of Systemic Sclerosis with Scleroderma Renal Crisis

Scleroderma renal crisis is a serious acute complication arising in the setting of systemic sclerosis. Timely recognition and immediate treatment at the point of diagnosis are central to management of this condition.

Clinical scenario: This protocol applies to patients with systemic sclerosis who develop scleroderma renal crisis — an acute presentation requiring urgent, diagnosis-driven intervention without delay.
Treatment approach: Management centres on ACE inhibitors, which are indicated immediately at the time of diagnosis. The complete protocol — covering agent selection, sequencing, and the full clinical pathway — is available via the link below.

References

DOI: 10.1136/ard-2024-226430

ACE inhibitors should be used immediately at diagnosis of scleroderma renal crisis.

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