Sublingual gland cancer
ICD-10 C08.1 · ICD-11 2B68&XA51Q9

Treatment of Sublingual Gland Cancer with Distant Metastasis (M1)

This protocol addresses sublingual gland cancer presenting with distant metastasis (M1 disease). At this stage the disease is no longer localised, and systemic management becomes the primary consideration.

In recurrent or metastatic (R/M) sublingual gland cancer, systemic treatment is challenging but can be urgent, depending on tumour subtype and behaviour. The extent and pace of distant spread guide the urgency and choice of approach.

Systemic therapy for this setting involves platinum-based palliative chemotherapy. In select cases where an actionable molecular target is identified, targeted therapy may also be considered — the full structured regimen includes further options and selection criteria.

Full regimen available below
References
DOI: 10.1016/j.esmoop.2022.100602
In case of R/M disease, systemic treatment is challenging but can be urgent, depending on tumour subtype and behaviour.
Consider platinum-based palliative ChT [III, B].
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