Treatment of Strongyloidiasis: First-Line Oral Antiparasitic Therapy
Clinical Scenario
Patients with a positive stool examination for Strongyloides and persistent symptoms require prompt antiparasitic treatment. Both acute and chronic strongyloidiasis are treatment indications.
Treatment Goal
Clearance of infection, confirmed by follow-up stool examination performed 2–4 weeks after the completion of therapy, in patients with positive stool findings and persistent symptoms.
Treatment Approach — partial overview
Two oral antiparasitic agents are available in the United States for first-line treatment of acute and chronic strongyloidiasis. The preferred agent and its alternative differ in dosing schedule and duration.
Full regimen details, dosing, and algorithm available in the structured protocol below.
References
- Two drugs are available in the United States to treat acute and chronic strongyloidiasis.
- Both oral ivermectin and oral albendazole is available for human use in the United States.
- In patients with positive stool examination for Strongyloides and persistent symptoms, follow-up stool exams should be performed 2–4 weeks after treatment to confirm clearance of infection.
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