Streptococcal toxic shock syndrome (STSS) is a severe, rapidly evolving condition. Selecting the appropriate first-line management approach requires careful review of the evidence and individual clinical context.
The protocol includes consideration of an adjunctive immunoglobulin-based intervention, assessed on an individual basis depending on the clinical situation. The full criteria, decision pathway, and complete regimen are available in the structured protocol below.
These findings pointed at possible importance of antibodies in the protection against invasive diseases and suggested that addition of IV polyclonal immunoglobulins (IVIG) to the treatment may be useful as an adjunctive therapy.
Therefore, the use of IVIG in STSS cannot be routinely recommended and should be discussed on a case-by-case basis.
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