Treatment of Streptobacillosis in a Child Under 18 with Rat Bite Fever (Not Penicillin-Allergic)
This protocol applies to paediatric patients under 18 years of age diagnosed with Streptobacillosis (rat bite fever) who have no known penicillin allergy. Age is a primary determinant of the treatment approach in this scenario.
Clinical Scenario
A child under 18 years presenting with rat bite fever confirmed as Streptobacillosis, with penicillin allergy ruled out. The patient's age shapes both the choice and the dosing strategy for the recommended regimen.
Treatment Approach
For this population, the guideline recommends a penicillin-based antibiotic course. The full protocol specifies the route, sequencing, weight-adjusted dosing, and duration — access the complete structured regimen below.
References
DOI: 10.1128/CMR.00016-06
Children should receive 20,000 to 50,000 IU/kg of body weight/day (12 to 30 mg/kg/day) of intravenous penicillin G for 5 to 7 days, followed by 7 days of oral penicillin V, 25 to 50 mg/kg/day (maximum, 3 g/day) divided four times per day.
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