Treatment of Stomach Cancer with Oligometastases Confined to the Ovary
When gastric cancer spreads in a limited pattern — with metastases restricted to the ovary — the clinical situation differs meaningfully from widespread metastatic disease and may warrant a distinct management approach in carefully selected patients.
Clinical scenario: Gastric cancer with oligometastases confined to the ovary (ovarian mass). The protocol addresses this specific pattern of limited ovarian involvement and the patient selection considerations it entails.
Approach: In selected patients, the strategy involves a surgical intervention targeting both the primary gastric tumour and the ovarian lesion, alongside systemic therapy. The complete selection criteria, surgical details, and systemic components are available in the full protocol.
References
DOI: 10.5230/jgc.2025.25.e11
- Radical gastrectomy, oophorectomy, and systemic therapy could be considered for selected gastric cancer patients with oligometastases in the ovary.
- For ovarian metastasis, 3 retrospective studies were included in the meta-analysis, showing better survival in the metastasectomy group (HR, 0.45; 95% CI, 0.34 to 0.59, P<0.001).
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