Gastric cancer presenting with oligometastases confined to the liver represents a specific clinical scenario in which the hepatic compartment is the sole site of distant spread. This pattern of disease defines a distinct patient population and informs how management is approached.
This protocol applies to patients with gastric cancer and oligometastatic disease limited to the liver. Careful patient selection is a defining feature of eligibility for the approach described in the full protocol.
For appropriately selected patients, management involves a combined surgical and systemic strategy. The complete regimen, selection criteria, and sequencing are detailed in the structured protocol.
DOI: 10.5230/jgc.2025.25.e11
Radical gastrectomy, metastatectomy and systemic therapy may be considered for selected gastric cancer patients with oligometastases in the liver.
The meta-analysis showed that radical gastrectomy with hepatectomy plus chemotherapy provided a survival benefit compared to chemotherapy alone (HR, 0.27; 95% CI, 0.12 to 0.62; P=0.002).
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