What Is the Treatment of Spleen Abscess? Antibiotic Therapy and Percutaneous Drainage

Clinical scenario

A splenic abscess is a focal suppurative collection within the spleen that requires prompt inpatient management. All patients with a confirmed diagnosis require hospitalisation to initiate systemic treatment and plan source control.

Treatment approach

Management combines extended-term antibiotic therapy — selected and reviewed on the basis of blood cultures and, where obtainable, abscess cultures — with image-guided intervention for source control. The interventional component involves ultrasound-guided percutaneous catheter drainage, with structured cavity lavage and monitoring until healing is confirmed.

The complete sequencing, catheter management details, antibiotic strategy, and decision points are in the full protocol.

Treatment goal

Healing of the splenic abscess, confirmed on follow-up ultrasound.