Spinal cord ependymoma
ICD-10 C72.0 · ICD-11 2A00.0Y&XH1511&XA0V83

Treatment of WHO Grade II Ependymoma of the Spinal Cord

Clinical Scenario

This protocol covers the management of WHO grade II ependymoma of the spinal cord — a specific histological classification that directly determines the treatment strategy and post-operative decision-making.

Treatment Approach

Management centres on surgical intervention aimed at maximal removal of the spinal cord tumor. The extent of resection achieved at surgery is a pivotal factor in determining what follows.

The complete evidence-based regimen — including post-surgical management steps and their criteria — is available in the full structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1093/neuonc/nox166

Gross total resection is the goal of spinal ependymoma surgery.

In case of WHO grade II ependymomas following gross total resection, a watch-and-wait strategy is recommended.

In case of incomplete resection of a WHO grade II ependymoma, postoperative local radiotherapy is recommended with doses of 45–54 Gy.

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