Treatment of Solid Papillary Carcinoma of Breast with Evidence of Invasion in Male Patients with Oestrogen Receptor-Positive Disease

This protocol applies to solid papillary carcinoma of the breast with evidence of invasion arising in a male patient whose tumour is oestrogen receptor (ER) positive. Male sex combined with ER-positive status defines a distinct clinical population requiring a specific adjuvant strategy.

The patient is male with confirmed oestrogen receptor-positive breast cancer. Both characteristics together — male sex and ER positivity — are the defining features that determine the treatment direction outlined in this protocol.

Adjuvant hormonal therapy is central to managing this scenario. The full protocol specifies which agent is recommended, the treatment duration, and the supporting evidence. Access the complete regimen below.