Treatment of SIBO in Intestinal Methanogen Overgrowth (Methane on Breath Testing)

Small intestinal bacterial overgrowth presenting with methane on breath testing is now defined differently from other SIBO patterns and is termed intestinal methanogen overgrowth (IMO). This distinction carries specific management implications.

Clinical scenario: Methane on breath testing is defined differently and is now termed intestinal methanogen overgrowth. Managing so-called IMO requires a targeted approach specific to this presentation.

Treatment approach — partial overview

The protocol for intestinal methanogen overgrowth involves a combination regimen of neomycin and rifaximin. The complete dosing, duration, and sequencing are available in the full structured protocol.

Instant Access to Structured Evidence-Based Regimens

References

Methane on breath testing is defined differently and now termed intestinal methanogen overgrowth.
How does one manage so-called intestinal methanogen overgrowth?
One uncontrolled trial suggested that the combination of neomycin and rifaximin might be effective.

DOI: 10.1053/j.gastro.2020.06.090

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