A patient presents with a skin furuncle showing signs that extend beyond a localised lesion — fever, regional lymphadenitis, or surrounding cellulitis indicate systemic involvement and guide the treatment approach.
When systemic symptoms develop alongside a furuncle, systemic antibiotic therapy is indicated. Oral antibiotic options are available; the specific selection and duration are defined in the full structured protocol and depend on the clinical picture.
Resolution of the skin lesion and full regression of signs of inflammation — systemic antibiotics are continued until both endpoints are met.