Sick sinus syndrome
ICD-10 I49.5 ICD-11 BC80.20

Treatment of Sick Sinus Syndrome in Syncope with Documented Asymptomatic Pauses >6 Seconds Due to Sinus Arrest

This protocol addresses a specific presentation of sick sinus syndrome: patients who experience syncope (fainting) in whom monitoring has captured asymptomatic sinus pauses exceeding 6 seconds due to sinus arrest — a documented electrophysiological finding that guides management.

Syncope with documented asymptomatic pause(s) >6 s due to sinus arrest. The key finding is objective rhythm documentation linking the sinus node dysfunction to the syncopal episodes.

Reduction of recurrent syncope — absence of further syncopal events.

A rhythm-based intervention targeting the underlying sinus node abnormality is indicated to prevent further episodes. The complete evidence-based regimen — including device selection criteria, programming parameters, and follow-up considerations — is available in the full protocol.

Full protocol details, including the structured regimen and evidence grading, are behind the link below.

References

DOI: 10.1093/eurheartj/ehab364

In patients with syncope, cardiac pacing may be considered to reduce recurrent syncope when asymptomatic pause(s) >6 s due to sinus arrest is documented.

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