This protocol applies to male patients with Sheehan syndrome presenting with central hypogonadism and low serum testosterone. Central hypogonadism in males manifests with low serum testosterone levels and features of testosterone deficiency and/or impaired spermatogenesis.
For eligible adult males in this scenario, the structured regimen centres on a hormonal replacement strategy directed at the testosterone deficit — the complete eligibility criteria, clinical parameters, and step-by-step protocol are available in the full regimen below.
DOI: 10.1210/jc.2016-2118
Central hypogonadism in males manifests with low serum T levels and features of T deficiency and/or impaired spermatogenesis.
We suggest T replacement for adult males with central hypogonadism and no contraindications in order to prevent anemia related to T deficiency; reduce fat mass; and improve bone mineral density (BMD), libido, sexual function, energy levels, sense of well-being, and muscle mass and strength.
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