Treatment of Secondary Hyperparathyroidism with a Single Enlarged Parathyroid Gland (>0.5 cm³)

Clinical Scenario

This protocol applies to patients with secondary hyperparathyroidism in whom imaging identifies only one enlarged parathyroid gland with a volume exceeding 0.5 cm³. This specific anatomical finding defines the population and guides the choice of intervention.

Approach

In this setting — alongside available medical and surgical options — an interventional, image-guided approach targeting the single enlarged gland is indicated. The full regimen specifies the technique, patient selection criteria, and procedural details.

Complete protocol with full clinical guidance available below.

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References

DOI: 10.3389/fendo.2023.1169793

In addition to the medical and surgical treatments, interventional treatment such as ultrasound-guided percutaneous ethanol injection (PEIT) is indicated for patients with only one enlarged PTG with a volume of >0.5 cm³.

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