Treatment of Schistosomiasis in Chronic Genitourinary Disease Caused by Schistosoma haematobium with Eggs Detected in Urine

Chronic genitourinary schistosomiasis due to Schistosoma haematobium presents with haematuria, dysuria, and obstructive uropathy, with diagnosis confirmed by egg detection in urine. This page outlines the clinical context and points to the structured treatment protocol.

Clinical Scenario

This scenario involves chronic infection with S. haematobium affecting the genitourinary tract. Key findings include haematuria, dysuria, and obstructive uropathy, with eggs demonstrable in urine. Associated complications can include bladder malignancy and female infertility.

Treatment Approach

This is a first-line protocol. The regimen is centred on an antiparasitic agent — praziquantel — given in a structured multi-dose schedule across a defined treatment period. Full dosing details, dose intervals, and the complete treatment timeline are available in the protocol.

Treatment Goals

No vital eggs detectable in urine at 3 months post-treatment — persistence indicates treatment failure or reinfection.
Eosinophilia fully resolved by 6 months post-treatment.

Instant Access to Structured Evidence-Based Regimens

References

Asymptomatic genitourinary S.: haematuria, dysuria, obstructive uropathy, bladder malignancy, female infertility*
Egg detection in urine (S. h.) or faeces (other S. spp.)
S. h., S. man., S. i.: 60 mg/kg/d p.o. (in 2 or 3 doses) on day 0 and on day 21‑30
Detection of vital eggs 3 months after treatment indicates treatment failure or reinfection.
Eosinophilia should be cleared at 6 months after treatment

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