Treatment of Sarcoidosis with Lacrimal Gland Granulomas and Keratoconjunctivitis Sicca (Dry Eye Syndrome)

Sarcoidosis can involve the lacrimal glands, where granulomatous infiltration disrupts tear production and leads to keratoconjunctivitis sicca — a form of dry eye syndrome that requires specific ocular surface management distinct from general sarcoidosis treatment.

Clinical scenario: Sarcoidosis with lacrimal gland granulomas resulting in keratoconjunctivitis sicca. Granulomatous involvement of the lacrimal glands reduces tear secretion, placing the conjunctiva at ongoing risk and requiring active moisture maintenance.

Management approach: This scenario is addressed with targeted topical measures directed at the ocular surface. The full structured protocol details the complete range of interventions and their use — access it below.

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References

Lacrimal gland granulomas can lead to keratoconjunctivitis sicca, which is best managed with artificial tears to keep the conjunctiva moist, lacrimal punctal plugs and/or topical cyclosporine.

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