Treatment of Sarcoidosis with Anterior Uveitis

Clinical Scenario

This protocol covers the management of sarcoidosis in patients who develop anterior uveitis — inflammation of the front segment of the eye. This ocular complication requires directed therapy to control local inflammation and prevent intraocular scarring.

The Condition

Anterior uveitis in sarcoidosis is often manageable with local ocular therapy. The priority is suppressing intraocular inflammation and avoiding structural damage. When local control is insufficient, systemic treatment becomes necessary.

Treatment Approach

The regimen centres on corticosteroid-based therapy, which may be delivered locally to the eye or systemically depending on severity. When corticosteroids alone are insufficient to control the disease, corticosteroid-sparing agents may be added — the full criteria, sequencing, and options are contained in the structured protocol.

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References

Anterior uveitis usually can be managed with local therapy using corticosteroid eye drops to suppress inflammation and cycloplegic eye drops to suppress pain and avoid intraocular scarring.
In some cases, periocular corticosteroid injections and long-term intraocular corticosteroid implants also have been used.
If greater than 10 mg prednisone is needed to control the disease, then corticosteroid-sparing drugs should be used.

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