Reversible posterior leukoencephalopathy syndrome
ICD-10 I67.8; I67.4 · ICD-11 8B22.Y.1

Treatment of Reversible Posterior Leukoencephalopathy Syndrome in Eclampsia During or After Pregnancy

Clinical Scenario

This protocol addresses posterior reversible encephalopathy syndrome (PRES) occurring in the setting of eclampsia during or after pregnancy. Diagnosis is based on typical clinical manifestations in combination with neuroimaging characteristics, interpreted within the obstetric context.

Treatment Approach

Management in this scenario involves an intravenous agent as the treatment of choice, directed at both hypertension and seizure control. Treatment selection is guided by careful consideration of maternal and fetal health throughout.

The complete structured regimen — including sequencing, decision points, and monitoring — is available via the full protocol.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1056/NEJMra2114482

The diagnosis of PRES with eclampsia during or after pregnancy is based on typical clinical manifestations and neuroimaging characteristics.

In consideration of fetal and maternal health, the treatment of choice for hypertension and seizures has generally been intravenous magnesium sulfate.

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