Reversible posterior leukoencephalopathy syndrome (RPLS) can arise in the setting of severe renal compromise. When marked renal failure is present, the underlying renal dysfunction requires direct and timely intervention as part of the overall management strategy.
This protocol addresses patients with RPLS in the context of marked renal failure — a specific sub-population in which renal status is a central driver of management priorities.
Management in this setting involves a renal replacement intervention. The complete sequencing, timing criteria, and procedural details are available in the full structured regimen.
DOI: 10.1136/practneurol-2021-003194
Those with marked renal failure need prompt dialysis.
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