Respiratory alkalosis
ICD-10 E87.3 · ICD-11 5C74.0

Treatment of Respiratory Alkalosis with Primary Hypocapnia in Dialysis Patients During Acute Illness

Dialysis patients who develop an acute illness may experience primary hypocapnia, producing respiratory alkalosis. In this population, the clinical priority is minimizing the degree of alkalemia while accounting for the constraints of the dialysis setting.

This protocol applies to patients currently receiving dialysis in whom an acute illness drives primary hypocapnia, resulting in respiratory alkalosis. The dialysis-dependent state directly shapes the management approach.

Primary hypocapnia Acute illness Receiving dialysis

Minimizing the degree of alkalemia in the context of dialysis-related management.

Management involves an adjustment to the dialysate composition — specifically targeting the bicarbonate component — to counteract the alkalemic state. The complete protocol, including specific parameters and clinical decision points, is available in the structured regimen.

References

DOI: 10.1053/j.ajkd.2023.02.004

A low dialysate HCO3− concentration is effective in minimizing the degree of alkalemia in patients receiving dialysis in whom an acute illness causes primary hypocapnia.

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