Renal cell carcinoma
ICD-10 C64 · ICD-11 2C90

Treatment of Advanced or Metastatic Chromophobe Renal Cell Carcinoma

Chromophobe renal cell carcinoma is a distinct histological subtype of RCC. Once disease reaches an advanced or metastatic stage, this subtype requires its own evidence-based treatment framework, separate from more common RCC histologies.

Clinical scenario Advanced or metastatic chromophobe renal cell carcinoma — a rare RCC subtype in which systemic therapy selection follows dedicated guidance.
Treatment overview Several systemic therapy options are recognised for advanced chromophobe RCC, encompassing both single-agent and combination approaches. Which option applies, and in what context, is defined in the full structured protocol — not summarised here.
Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.annonc.2024.05.537

  • Sunitinib, pazopanib, lenvatinib plus everolimus, everolimus and lenvatinib plus pembrolizumab may be used for advanced chromophobe RCC.
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