This protocol applies to patients who have recently started dialysis — within the first three months — and who have renal artery atherosclerosis alongside a kidney that is currently nonfunctioning but may still retain viability.
Identifying this subgroup is clinically significant: a nonfunctioning kidney is not necessarily a permanently lost kidney, and the duration of dialysis is a key consideration when evaluating the potential for recovery.
The defining feature of this scenario is a new dialysis patient (less than 3 months on renal replacement therapy) who presents with a nonfunctioning but possibly viable kidney in the context of renal artery atherosclerosis.
The possibility of kidney viability — sometimes described as a "hibernated" state — is the central clinical question that drives the treatment approach in this situation.
DOI: 10.1053/j.ajkd.2021.06.025
New (<3 mo) dialysis patient with nonfunctioning but possibly viable kidney.
However, occasional patients may have nonfunctioning but still viable (ie, "hibernated") kidneys that may recover function after revascularization and/or regenerative therapies.
Currently, dialysis patients with reversible kidney damage related to severe ARVD who may benefit from revascularization are often denied this possibility because of our inability to identify them and also because of the decrease in use of renal revascularization procedures following the results of the RCTs.
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