Remnant gastric cancer (RGC) arises in the residual stomach following prior gastric surgery. When identified at an early or superficial stage, management focuses on achieving definitive local control of the lesion within the remnant organ — potentially without radical re-operation.
Success is defined by achieving macroscopic complete resection of the lesion with no lymphovascular infiltration observed on pathologic examination — criteria that may allow avoidance of further surgical intervention in selected patients.
DOI: 10.3389/fonc.2024.1457564
Endoscopic resection is first-line therapy in the management of superficial neoplasms throughout the gastrointestinal tract, as well as an increasingly viable therapeutic alternative in the resection of selected small deep lesions throughout the upper and lower gastrointestinal tract.
Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are two well-known endoscopic resection procedures used for advanced gastrointestinal lesions.
In the past, remnant gastric cancer (RGC) was commonly detected at an advanced stage where radical surgical resection was considered the only method for achieving cure. However, completion gastrectomy does not improve survival outcomes compared with endoscopic resection and may even adversely affect the long-term outcomes of patients with early RGC.
Additional surgical resection might be avoided in selected cases that can even present noncurative features after endoscopic resection if macroscopic complete resection is achieved and lymphovascular infiltration is not observed.
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