Pyogenic granuloma
ICD-10 L98.0 · ICD-11 2F26

What is the treatment of pyogenic granuloma requiring surgical intervention?

Pyogenic granuloma is a benign vascular lesion that frequently requires definitive treatment when it causes significant bleeding, discomfort, or deep tissue involvement. The choice of surgical approach depends on lesion location, extent, and whether a tissue specimen is needed.

This protocol applies when the lesion has deep extensions, causes significant bleeding or discomfort, requires precise tissue removal, or when histological confirmation is needed. Specific anatomical considerations — particularly for gingival lesions — influence the selection among available surgical techniques.
Surgical excision is the preferred, most effective first-line approach. Several excision techniques are available depending on the lesion's characteristics and location — for gingival lesions, a specific modified technique has been shown to achieve meaningfully higher success rates than simple excision alone. The full selection criteria, technique sequence, and post-procedure considerations are detailed in the complete protocol …
Complete resolution of the pyogenic granuloma after a single session.
References
DOI: 10.1097/GOX.0000000000006160

Surgical excision, particularly in intraoral lesions, head and neck, upper extremities, and digits proves highly effective, achieving a 98% resolution after a single session.

In cases of gingival PGs, a retrospective study demonstrated that modified excision with deep curettage surpasses simple excision, achieving a nearly 15% higher success rate in 28 patients.

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