Pulmonary veno-occlusive disease
ICD-10 I28.8 · ICD-11 BB01.01

First-Line Treatment of Pulmonary Veno-Occlusive Disease

Pulmonary veno-occlusive disease (PVOD) is a rare, severe form of pulmonary hypertension characterised by progressive obstruction of the pulmonary venous circulation. First-line management focuses on stabilising the patient's condition and preventing avoidable deterioration.

Clinical context Managing PVOD requires careful attention to haemodynamic stability and respiratory status. The structured protocol addresses the key clinical priorities from initial presentation.
Treatment approach (partial) The first-line protocol centres on general and supportive measures — including targeted respiratory support for hypoxaemic patients and strategies to optimise fluid balance. Full regimen, clinical decision points, and guidance on anticoagulation are detailed in the complete protocol →
Instant Access to Structured Evidence-Based Regimens

References

  1. General and supportive measures include oxygen supplements in hypoxemic patients to prevent worsening PH from hypoxic pulmonary vasoconstriction.
  2. Diuretics should be used to optimize volume status.
  3. There is no proposed recommendation for anticoagulation in PVOD patients.
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