This protocol applies to patients with pulmonary hypertension secondary to left heart disease who have severe tricuspid regurgitation. Severe TR drives significant volume overload, markedly increases right ventricular workload, and promotes maladaptive right-heart remodelling — resulting in symptomatic right heart failure and impaired survival.
The protocol centres on a transcatheter tricuspid valve-based intervention targeting the underlying regurgitation — the complete regimen, eligibility criteria, and step-by-step algorithm are available via the full protocol.
DOI: 10.1093/eurheartj/ehac237
Severe TR is associated with volume overload, increased RV work-load, and maladaptive remodelling, leading to symptomatic right HF and impaired survival.
Transcatheter tricuspid valve interventions have recently emerged, aiming at reducing TR and RV volume overload.
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