Pulmonary hypertension secondary to left heart disease
ICD-10 I27.2 · ICD-11 BB01.1

Treatment of Pulmonary Hypertension Secondary to Left Heart Disease in Mitral Stenosis or Mitral Regurgitation

Clinical scenario

This protocol applies to patients with pulmonary hypertension secondary to left heart disease who have mitral stenosis or mitral regurgitation. Both conditions regularly lead to post-capillary pulmonary hypertension, driven by chronically elevated left-sided filling pressures transmitted to the pulmonary circulation.

Treatment approach

The management strategy involves a surgical or interventional approach directed at the mitral valve. The specific patient selection criteria, procedural pathway, and sequencing criteria are detailed in the full structured protocol.

Clinical goals
  • Reduction in mean pulmonary arterial pressure
  • Reduction in pulmonary arterial wedge pressure
  • Improvement in cardiac index
Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1093/eurheartj/ehac237

Both mitral stenosis and regurgitation regularly lead to post-capillary PH.

Reducing mitral regurgitation according to the recommendations of the 2021 ESC/EACTS Guidelines for the management of valvular heart disease has a crucial role in improving haemodynamics in patients with HFrEF, as this reduces mPAP and PAWP and improves the CI.

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