Tratamento da Trombose Venosa Mesentérica Aguda com Peritonite
Quando a trombose venosa mesentérica aguda é complicada por peritonite ou sinais peritoneais na apresentação, isso sinaliza progressão da isquemia que exige uma resposta clínica urgente e estruturada, distinta dos casos não complicados.
Cenário clínico
Trombose venosa mesentérica aguda com peritonite ou sinais peritoneais na apresentação. Febre e sinais peritoneais são sugestivos de progressão da isquemia para infarto intestinal, indicando que o manejo conservador isolado é insuficiente.
References
DOI: 10.1016/j.ejvs.2025.06.010
- Peritonitis
- Patients with persisting or worsening symptoms, organ failure, and those with perforation or signs of peritonitis require open surgical intervention.
- Fever and peritoneal signs are suggestive of progression of ischaemia to bowel infarction.
- The aim of surgery is to remove irreversibly ischaemic bowel and preserve as much bowel as possible.
- Anticoagulation with unfractionated or low molecular weight heparin as first line therapy is recommended for all patients with acute mesenteric vein thrombosis.
- Pain control, fluid and electrolyte supplementation, and bowel rest should be initiated immediately.
- Anticoagulation for three to six months with a vitamin K antagonist or low molecular weight heparin is recommended for all patients with acute mesenteric vein thrombosis.
- Anticoagulation for three to six months with a direct oral anticoagulant as an alternative to a vitamin K antagonist or low molecular weight heparin may be considered for all patients with acute mesenteric vein thrombosis.