Psoriasis Treatment in Patients with Obesity (BMI ≥30 kg/m²)

When psoriasis occurs alongside obesity — defined as a body mass index of 30 kg/m² or higher — managing body weight becomes a clinically relevant part of the overall care plan. Evidence-based guidelines address this patient group specifically.

Patient presents with psoriasis and obesity (BMI ≥30 kg/m²). Guidelines recommend annual assessment of obesity status in patients with moderate-to-severe psoriasis. Those with obesity class 1 or higher and/or abdominal obesity should be referred to their primary care physician for further education and evaluation.

The protocol for this scenario centres on a structured low-energy dietary intervention as a standard weight management measure. The full details of the regimen — including its sequencing and specific parameters — are available in the complete protocol.

  • Modest reduction in Psoriasis Area Severity Index (PASI)
  • Meaningful weight loss
  • Improvement in Dermatology Life Quality Index (DLQI)

References

DOI: 10.1016/j.jaad.2018.11.058

Patients with moderate-to-severe psoriasis should have their obesity status determined annually.

Patients of obesity class 1 or higher (BMI >30 kg/m²) and/or abdominal obesity should be referred to their primary care physician for further education and evaluation.

60 obese psoriatic patients were enrolled in a prospective randomized clinical trial and allocated to receive either a low-energy diet (800–1000 kcal/day) for 8 weeks or to eat ordinary healthy foods.

These results indicate a low-energy diet (with subsequent weight loss) might cause a modest reduction in PASI and improve a patient’s QoL.

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