Treatment of Psoriasis in Nail Psoriasis

Psoriasis affecting the nails — nail psoriasis — is a specific presentation that may require targeted intervention, particularly when lesions are localised, very thick, or nonresponding to initial treatment.

Clinical Scenario

This protocol addresses psoriasis presenting as nail psoriasis. It is relevant when nail lesions are localised and either do not respond adequately or present as very thick nail changes.

Treatment Approach

For localised nail lesions that are nonresponding or very thick, an intralesional corticosteroid approach is one option addressed in this protocol.

The complete regimen — including specific agents, dosing, frequency, and the full clinical decision pathway — is available in the structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.jaad.2020.07.087

Topical tazarotene can be used for the treatment of nail psoriasis.

Additionally, intralesional corticosteroids can be used for localized nonresponding or very thick lesions on glabrous skin, scalp, nails, palms, and soles.

Triamcinolone acetonide in a dose up to 20 mg/mL can be used every 3 to 4 weeks.

View source ↗