Protein S deficiency

ICD-10 D68.5 · ICD-11 3B61.0Y.3

Treatment of Protein S Deficiency in Pregnancy

This protocol addresses Protein S deficiency in the specific context of pregnancy — covering the management approach for a patient with an established diagnosis of Protein S deficiency who is pregnant.

Clinical Scenario

The patient is a pregnant woman with a pre-existing diagnosis of Protein S deficiency — that is, the condition was identified prior to conception. Pregnancy in this setting requires structured clinical management.

Treatment Approach

Management involves a prophylactic anticoagulation strategy. Low molecular weight heparin is central to the approach used in this scenario.

The complete regimen — including dosing, duration, monitoring parameters, and the full clinical algorithm — is available in the structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1186/s12959-026-00861-w

a PS deficient pregnant woman (diagnosed before pregnancy) was treated with prophylactic LMWH

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