This protocol addresses prolactinoma in female patients who are currently pregnant or who are considering pregnancy. The clinical picture requires careful evaluation of both the adenoma and the patient's reproductive goals.
Women with prolactinoma who desire pregnancy should be counselled about both medical and surgical treatment options. Medical treatment with dopamine agonists is the first choice of therapy for women with prolactinoma desiring pregnancy, based on current evidence.
Management centres on decisions around dopamine agonist therapy — including whether to continue, discontinue, or re-initiate it in the context of pregnancy. Adenoma size is a key factor shaping the approach taken.
DOI: 10.1038/s41574-023-00886-5