This protocol applies to patients with prolactinoma in whom chronic kidney disease (renal failure) is present alongside hyperprolactinaemia and hypogonadism.
Chronic kidney disease (renal failure) with co-existing hyperprolactinaemia and hypogonadism. Treatment selection is informed by this combination and by the patient's clinical symptoms.
Treatment may involve dopamine agonist therapy, depending on clinical symptoms. The complete options and clinical algorithm are detailed in the full protocol.
Lowered serum prolactin levels, increased testosterone levels, and restored sexual potency.
DOI: 10.1038/s41574-023-00886-5
Treatment of hypogonadism and underlying hyperprolactinaemia by dopamine agonist therapy or sex hormone replacement might be considered in patients with CKD, depending on clinical symptoms (weak).
Bromocriptine effectively lowers serum levels of prolactin, increases levels of testosterone and restores sexual potency in men with CKD and hyperprolactinaemia.
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