Treatment of Primary Pulmonary Lymphoma in Lymphomatoid Granulomatosis — Localised Pulmonary Form

When primary pulmonary lymphoma occurs in the setting of lymphomatoid granulomatosis and is confined to a localised pulmonary form, the clinical situation calls for a specific approach that differs from more extensive disease.

Clinical scenario Primary pulmonary lymphoma arising in lymphomatoid granulomatosis, presenting as a localised pulmonary form. This is a distinct subgroup with its own treatment considerations.
Treatment overview partial summary — full protocol below Localised presentations have been treated with locoregional interventions including surgical and radiation-based approaches. In certain cases, a more conservative strategy may also be considered. The complete treatment algorithm and all decision criteria are in the full structured protocol.
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References

Localised pulmonary forms have been successfully treated with surgery and/or radiotherapy.

Simple monitoring may also be appropriate, as spontaneous complete remissions have been observed.

DOI: 10.1183/09031936.02.00404102

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